Blood Tests
Below are typical blood test values and goals for both MtF and FtM hormone replacement therapy. Always consult a qualified medical provider when possible.
MtF Blood Tests
| Test Name |
Typical Range |
Recommended Range (on HRT) |
Notes |
| Testosterone | 8–29 nmol/L | <2 nmol/L | Suppressed to female range |
| Estradiol (E2) | 70–530 pmol/L (female) | 200–500 pmol/L | Goal is mid-range female |
| SHBG | 18–144 nmol/L | Monitor only if using oral estradiol | Can affect free hormone levels |
| Prolactin | 100–500 mIU/L | Under 700 mIU/L | May rise slightly on HRT |
| ALT/AST | Up to 40 U/L | Same as cis females | Liver function monitoring |
FtM Blood Tests
| Test Name |
Typical Range |
Recommended Range (on HRT) |
Notes |
| Testosterone | 8–29 nmol/L | 10–30 nmol/L | Target male physiological range |
| Estradiol (E2) | 70–530 pmol/L (female) | <100 pmol/L | Suppressed, but not always to 0 |
| Hematocrit | 0.36–0.47 (female) | 0.45–0.54 | Increases with testosterone use |
| ALT/AST | Up to 40 U/L | Same as cis males | Liver function monitoring |
| LH/FSH | Varies | Suppressed | Not routinely monitored once stable |